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A quartet of mercenaries are lured to an ambush in South Sudan where their bodies fall on the ground after getting showered with bullets. A few minutes later, the four of them get up as if nothing happened and slay the strike force that just slaughtered them. The bloodbath is recorded on camera and sent to Steven Merrick (Harry Melling), a big pharma CEO who is keen to cash in on the group’s immortality. Escaping on a train, Andy (Charlize Theron), Booker (Matthias Schoenaerts), Joe (Marwan Kenzari), and Nicky (Luca Marinelli) dream of a young marine’s death and rebirth in Afghanistan. Nile Freeman (KiKi Layne) is confused as to what has just happened to her and is about to be flown to Germany to be tested and probably experimented on. Realizing that another immortal has just awakened, Andy comes to the rescue to introduce the newbie to the gang, but the pharmaceutical empire hunting them with the help of former CIA James Copley (Chiwetel Ejiofor) will not stop until they get their bounty.